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Page 1
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling.
Nat Cell Biol. 2021 Apr;23(4):377-390. doi: 10.1038/s41556-021-00654-5. Epub 2021 Apr 1.
Nat Cell Biol. 2021.
PMID: 33795873
Free PMC article.
Colorectal Cancer Modeling with Organoids: Discriminating between Oncogenic RAS and BRAF Variants.
Post JB, Roodhart JML, Snippert HJG.
Post JB, et al.
Trends Cancer. 2020 Feb;6(2):111-129. doi: 10.1016/j.trecan.2019.12.005. Epub 2020 Jan 21.
Trends Cancer. 2020.
PMID: 32061302
Review.
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Diverse BRAF Gene Fusions Confer Resistance to EGFR-Targeted Therapy via Differential Modulation of BRAF Activity.
Stangl C, Post JB, van Roosmalen MJ, Hami N, Verlaan-Klink I, Vos HR, van Es RM, Koudijs MJ, Voest EE, Snippert HJG, Kloosterman WP.
Stangl C, et al. Among authors: post jb.
Mol Cancer Res. 2020 Apr;18(4):537-548. doi: 10.1158/1541-7786.MCR-19-0529. Epub 2020 Jan 7.
Mol Cancer Res. 2020.
PMID: 31911540
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Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells.
Hindriksen S, Bramer AJ, Truong MA, Vromans MJM, Post JB, Verlaan-Klink I, Snippert HJ, Lens SMA, Hadders MA.
Hindriksen S, et al. Among authors: post jb.
PLoS One. 2017 Jun 22;12(6):e0179514. doi: 10.1371/journal.pone.0179514. eCollection 2017.
PLoS One. 2017.
PMID: 28640891
Free PMC article.
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CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition.
Post JB, Hami N, Mertens AEE, Elfrink S, Bos JL, Snippert HJG.
Post JB, et al.
Oncotarget. 2019 Feb 15;10(14):1440-1457. doi: 10.18632/oncotarget.26677. eCollection 2019 Feb 15.
Oncotarget. 2019.
PMID: 30858928
Free PMC article.
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